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Autoimmune Conditions

26 articles

New Rheumatoid Arthritis Guidelines Shift When to Add Biologics and JAK Inhibitors

Combining methotrexate with a biologic or JAK inhibitor nearly doubles rheumatoid arthritis remission odds, per a major JAMA review of 123 studies.

A Skin Patch That Repairs MS Nerve Damage Is Moving Toward Human Testing

A skin patch delivering low-dose theophylline to repair multiple sclerosis nerve damage is moving toward human clinical trials after promising mouse study.

First Oral Drug for Rare Muscle Disease Offers Hope Beyond Steroids

The FDA approved brepocitinib, the first oral drug for dermatomyositis, cutting steroid dependence and improving symptoms in as little as four weeks.

MS Diagnosis Gets a Powerful New Tool: How Brain Scans and Immune Markers Are Changing Detection

Microglia activation in MS lesions predicts disability progression, offering doctors a powerful new biomarker to personalize treatment before damage.

A Stroke Drug May Help Repair MS Damage: What Animal Studies Reveal

A stroke drug called nimodipine may reduce inflammation and repair myelin damage in multiple sclerosis, according to a review of animal studies.

Australia's MS Drug Review Could Reshape Treatment Access: Here's What Patients Need to Know

Australia's PBAC will review all PBS-listed multiple sclerosis medicines in 2026, with patient input shaping which treatments stay affordable and.

Which Rheumatoid Arthritis Drug Works Best? New Research Reveals a Surprising Answer

Rituximab outperforms other rheumatoid arthritis drugs for pain and fatigue relief, but a 99-study analysis finds treatment choice should match each.

FDA Clears First-Ever Human Trial of Oral MS Drug Designed to Repair Nerve Damage

The FDA has cleared Lucid-MS, the first oral multiple sclerosis drug designed to repair nerve damage rather than just suppress the immune system.

Why Lupus Patients Need to Keep Their Hydroxychloroquine Levels High to Prevent Heart Disease

Lupus patients with low hydroxychloroquine blood levels face 47% higher cardiovascular risk, a new Yale study finds; regular blood level monitoring is key.

Three Emerging Approaches to MS Treatment: From Immune Reset to Gut Bacteria

Three radical MS treatment approaches, from a one-time CAR T cell immune reset to gut bacteria supplements, could move beyond symptom management to tackle.

One JAK Inhibitor Shows Lower Shingles Risk Than Others for Rheumatoid Arthritis

Filgotinib showed one-tenth the shingles risk of tofacitinib in a real-world study of rheumatoid arthritis patients on JAK inhibitors.

NHS Approves Fampridine to Help MS Patients Walk Faster: What the Evidence Shows

NHS England now offers fampridine for multiple sclerosis patients, with 43% walking faster, but only those who respond after a trial period continue.

Lab-Grown 'Mini Brains' Offer New Hope for Repairing MS Damage

Australian researchers are using lab-grown mini brains to study myelin repair in multiple sclerosis, a disease with no current treatment to reverse nerve.

Scientists Discover a Protein That Could Protect Against Nerve Damage in MS

A protein called Piezo2, found in 73% of healthy myelin cells but only 50% in MS tissue, could offer a new way to preserve nerve protection in multiple.

How New MS Diagnostic Rules Could Speed Diagnosis but Reshape Clinical Trials

Updated MS diagnostic criteria could catch multiple sclerosis earlier, but experts warn of overdiagnosis risks and urgent need to redesign clinical trials.

New Psoriasis Pill Clears Hard-to-Treat Scalp and Nail Lesions in 77% of Patients

A new psoriasis pill called zasocitinib cleared scalp lesions in 77% of patients in Phase 3 trials, far outperforming existing oral treatments.

Type 1 Diabetes Is Now Treatable Before Symptoms Appear. Here's Why Screening Matters.

Type 1 diabetes can now be detected and treated before symptoms appear, but experts warn that inconsistent screening limits access to this breakthrough.

Why Women With Rheumatoid Arthritis Are Now Having Safer Pregnancies

Women with rheumatoid arthritis can now safely plan pregnancies, with 85% maintaining remission when kept on biologic medications throughout gestation.

A $7.49 Million Bet on MS: How Scientists Are Engineering Immune Cells to Reset the Disease

UCLA scientists are engineering immune cells that attack multiple sclerosis on two fronts, with $7.49M in funding to push the potential cure toward human.

After 15 Years, Two Patients With Severe Autoimmune Disease Remain Symptom-Free Without Medication

Two patients with a severe autoimmune disease remain symptom-free for over 15 years after a stem cell transplant fully replaced their immune systems.

A New Path Forward: How Scientists Are Teaching the Immune System to Accept Transplanted Organs

A German biotech has enrolled all 63 patients in a trial testing MIC-Lx, a cell therapy designed to end lifelong immunosuppression after kidney transplant.

First Systemic Treatment for Vitiligo Wins European Approval: What Patients Need to Know

Europe's first systemic vitiligo treatment is nearly here: upadacitinib showed 75% facial repigmentation in trials and awaits final EU approval.

Living Drugs Show Promise for Severe Autoimmune Diseases That Resist Standard Treatment

CAR T-cell therapy is achieving remission in severe autoimmune diseases like lupus and rheumatoid arthritis, with 83% of trial patients responding without.

When Autoimmune Disease Strikes at Peak Success: What Joe Manganiello's Health Battle Reveals

Joe Manganiello's memoir will reveal a seven-year autoimmune battle that attacked five body systems and required life-saving organ removal.

Celiac Disease May Raise Risk of a Serious Lung Condition: What You Need to Know

A new genetic study links celiac disease to pulmonary arterial hypertension, a serious lung condition, suggesting the autoimmune disorder's risks extend.

Scientists Discover a Radical New Way to Reset Autoimmune Disease: Erasing Immune Memory

Scientists used BiTE molecules to erase autoimmune disease at its root, reaching immune cells hiding in bone marrow where standard drugs cannot.