NIH agrees to review frozen grant applications for HIV prevention, LGBTQ+ health, and sexual violence research after legal challenge.
The National Institutes of Health (NIH) has agreed to individually review hundreds of scientific grant applications that were arbitrarily frozen or denied, including crucial research on HIV prevention, LGBTQ+ health, and sexual violence. This settlement resolves a lawsuit that challenged unlawful policy directives that put researchers' careers in limbo and stalled vital public health studies.
What Research Areas Will Benefit From This Decision?
The agreement covers grant applications addressing several urgent public health issues that directly impact sexual wellness and reproductive health. These studies were among those caught in the administrative freeze that affected researchers nationwide.
- HIV Prevention Research: Studies focused on preventing HIV transmission and improving treatment outcomes for affected communities
- LGBTQ+ Health Studies: Research examining health disparities and developing targeted interventions for LGBTQ+ populations
- Sexual Violence Prevention: Scientific investigations into preventing sexual assault and supporting survivors
- Alzheimer's Disease Research: Studies on aging and brain health, including alcohol use impacts
How Will the Review Process Work?
Under the settlement agreement, the NIH must use its standard scientific review process to evaluate each stalled application individually. The agency has committed to reviewing applications without reference to the previously unlawful policy directives that caused the freeze.
"Researchers deserve to have their work evaluated on its merits, not sidelined by political interference," said Olga Akselrod, senior counsel with the American Civil Liberties Union (ACLU) Racial Justice Program. "NIH has now agreed to review the stalled applications individually and in good faith, without applying the unlawful policy directives."
The agreement establishes clear deadlines for reviews based on when each application was originally submitted. Importantly, the close of Federal Fiscal Year 2025 will not prevent the NIH from reviewing or awarding any of these applications.
Why Does This Matter for Sexual Health Research?
This legal victory has significant implications for advancing sexual health research that could benefit millions of Americans. The frozen applications included studies that could lead to better sexually transmitted infection (STI) prevention strategies, improved contraception methods, and enhanced understanding of reproductive health disparities.
"This agreement allows my grant application, and many others, to move forward for review after an arbitrary and destructive freeze," said plaintiff Nikki Maphis, a postdoctoral researcher at the University of New Mexico who studies aging and brain health.
The lawsuit was filed by the ACLU, ACLU of Massachusetts, Protect Democracy, and other organizations on behalf of individual researchers and groups including the American Public Health Association and the International Union, United Automobile, Aerospace and Agricultural Implement Workers of America.
While this agreement resolves the immediate issue of stalled applications, the broader legal challenge continues. A U.S. District Court previously found the NIH directives unlawful, and oral arguments in the appeals process are scheduled for January 6, 2026.
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