New FDA-cleared updates to the Omnipod 5 insulin pump offer a lower 100 mg/dL target and fewer interruptions for better diabetes management.
The latest FDA-cleared enhancements to the Omnipod 5 insulin pump system promise to make diabetes management more precise and less disruptive for millions of Americans. These significant algorithm updates, announced by Insulet Corporation, introduce a lower 100 mg/dL target glucose option and reduce system interruptions that can interfere with daily life.
What Makes This Update Different?
The enhanced Omnipod 5 system now offers six customizable target glucose settings ranging from 100-150 mg/dL in 10 mg/dL increments, giving healthcare providers much more flexibility to tailor treatment. Previously, the lowest target was higher, but real-world evidence shows that lowering the glucose target increases time in range without meaningfully increasing dangerous low blood sugar episodes.
The upgraded algorithm also helps users stay in automated mode with fewer interruptions, even during prolonged high glucose events. This means less manual intervention and more seamless diabetes management throughout the day.
Who Benefits from These Changes?
The updates address the two most requested improvements from users and healthcare providers. The system is cleared for people aged 2 and older with type 1 diabetes and those 18 and older with type 2 diabetes.
- Tighter Control Seekers: Individuals wanting more precise glucose management can now target 100 mg/dL instead of higher levels
- Busy Families: Parents and patients experience fewer system interruptions that require immediate attention during work, school, or sleep
- Healthcare Providers: Doctors can customize treatment more precisely to help patients meet specific glucose goals
"These enhancements to the Omnipod 5 algorithm are a meaningful step forward. As a clinician, it's exciting to offer patients a system that not only supports strong clinical outcomes but also builds their confidence in managing diabetes daily," said Anita Swamy, MD, Pediatric Endocrinologist and Medical Director of the Chicago Children's Diabetes Center.
When Will These Updates Be Available?
The algorithm enhancements are expected to launch in the United States during the first half of 2026. This timeline allows Insulet to ensure proper rollout and training for healthcare providers who will be implementing these new features with their patients.
"This is the most significant algorithm advancement to our Omnipod 5 System since its launch in 2022," explained Eric Benjamin, Insulet Executive Vice President and Chief Operating Officer. "Every improvement we make is designed to strengthen clinical outcomes while making the Pod experience simpler, more personalized, and so seamless it disappears into everyday life."
For the estimated 37 million Americans living with diabetes, these updates represent a meaningful step toward more personalized and less intrusive diabetes management. The combination of tighter glucose control options and fewer daily interruptions could significantly improve quality of life for users and their families.
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